Apigenin

Apigenin Reviews

Apigenin (4′,5,7-trihydroxyflavone), primarily found in many plants, is a flavone (a subclass of bioflavonoids) that is the aglycone of several naturally occurring glycosides. It mainly exists in the plants of the family Asteraceae (daisy), the family Ruixiang, family Verbenaceae, and family Selaginella, and is widely distributed in vegetables and fruits in temperate regions, with celery being the most abundant. In foods and herbs, apigenin is often found in the more stable derivative form of apigenin-7-O-glucoside. Numerous studies both domestically and internationally have found that apigenin has various biological activities, including anti-tumor, cardiovascular and cerebrovascular protection, antiviral, and antibacterial properties.

How Apigenin Works

There are two main metabolic pathways of apigenin in the human body. One is to transform it into a substance called apigenin glucoside through the role of the liver. This substance is an anti diabetes substance that can reduce blood sugar and insulin levels. Another type is through the action of intestinal bacteria, converted into a substance called lignin or intestinal lipids, which is an antioxidant that can inhibit the carcinogenic substances produced by intestinal bacteria. In addition, it can also enhance the body’s anti-cancer ability by regulating the immune system.
It also has the function of reducing the damage caused by neuroinflammation and protecting nerve cells, as it can inhibit the production of inflammatory factors such as tumor necrosis factor- α (TNF)- α）、 Interleukin-1 β (IL-1) β）. It can also regulate fat metabolism, inhibit the differentiation and proliferation of adipocytes, promote the breakdown and consumption of fat, thereby reducing fat storage in the body, controlling weight, and preventing and treating diseases such as obesity, hyperlipidemia, and atherosclerosis.

Health Benefits of Apigenin

There are so many Health Benefits of Apigenin, including Anticancer, Lowering Blood Pressure, Mind-tranquilizin, Clearing Heat and Detoxifying, Beauty and Weight Loss and so on, here we will browes some of its important Health Benefits as below:
Anticancer
Apigenin is a powerful anti-cancer substance that can selectively induce cancer cell apoptosis without damaging normal cells. It can also block the development of cancer cells by inhibiting multiple processes such as proliferation, invasion, metastasis, and angiogenesis.
Lowering Blood Pressure
Apigenin is an effective blood pressure lowering substance that can lower blood pressure by dilating blood vessels, reducing vascular resistance. It can also lower blood pressure by inhibiting the activity of angiotensin converting enzyme (ACE) and reducing the production of angiotensin II. In addition, apigenin can also lower blood pressure by regulating potassium and sodium balance, promoting the excretion of excess sodium salts.
Mind-tranquilizin
Apigenin is a substance with sedative and calming effects, which can affect the synthesis and release of neurotransmitters, such as γ- Aminobutyric acid (GABA), serotonin (5-HT), dopamine (DA), etc., regulate the excitement and inhibition of the nervous system, alleviate emotional disorders such as anxiety, depression, and insomnia.
Clearing Heat and Detoxifying
Apigenin is a kind of substance with heat clearing and detoxification effects. It can prevent and cure various infectious diseases, such as pneumonia, pharyngitis, diarrhea and dermatitis, by inhibiting the growth and reproduction of bacteria, viruses, fungi and other microorganisms. It can also enhance the detoxification ability of the liver, promote the metabolism and excretion of toxins, purify the blood, improve liver function, and prevent diseases such as hepatitis, cirrhosis, and liver cancer.
Beauty and Weight Loss
Apigenin is a substance with beauty and weight loss effects. It can resist oxidation, eliminate free radicals in the body, delay aging, inhibit the generation of melanin, improve skin tone, increase skin elasticity and luster, and prevent skin problems such as wrinkles, spots, and acne.

Apigenin Side Effects

Not suitable for excessive consumption, apigenin is photosensitive and excessive consumption can lead to dermatitis.

Where to Buy High Quality Apigenin

Henan Steeda Industrial Co.,Ltd is a Reputed Manufacturer and Supplier Supplying High Quality Pharmaceutical, Nutraceutical and Cosmeceutical Ingredients. Apigenin is one of our most competitive ingredients with stocks available all year round. By providing high quality, we establish long-term relationships with our customers.

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