Caffeic Acid

Caffeic Acid Reviews

Caffeic acid, an organic acid, is classified as a hydroxinamic acid and is not related to caffeine. It is a yellow crystalline powder that is soluble in hot water and ethanol, and slightly soluble in cold water. Because caffeic acid is a key intermediate of lignin, one of the main components in the biosynthesis of plant biomass and its residues, it is widely present in various plants. In nature, caffeic acid exists in the bark of Eucalyptus globus, the barley grain Hordeum vulgare, the herb Dipsacus asperoids, and the freshwater fern Salvia molesta of the Mushroom Phellinus linteu. It can be safely used in cosmetics and has a wide range of antibacterial and antiviral activities.

How Caffeic Acid Works

Caffeic acid is prone to automatic oxidation. Glutathione, thiol compounds, or ascorbic acid have inhibitory effects on the browning and disappearance of caffeic acid, which is caused by the oxidation of ortho diphenol to ortho quinone. Chemical oxidation of caffeic acid with sodium periodate under acidic conditions produces dimers with furan structure (isomers of 2,5- (3 ‘, 4’ – dihydroxyphenyl) tetrahydrofuran 3,4-dicarboxylic acid). The use of horseradish peroxidase/hydrogen peroxide oxidation system can lead to the polymerization of caffeic acid.

Health Benefits of Caffeic Acid

There are so many Health Benefits of Caffeic Acid, such as Antiinflammatory, Hemostasis, Antioxidant and so on, here we will browes some of its important Health Benefits as below:
Antiinflammatory
Caffeic acid has immunomodulatory and anti-inflammatory activities, which can alleviate tissue damage and alleviate pain symptoms by inhibiting the release of inflammatory mediators. Caffeic acid can reduce aflatoxin production by over 95%, which is superior to other antioxidants. Caffeic acid can also block the cyclooxygenase pathway in arachidonic acid metabolism, reduce the synthesis of prostaglandin E2, and thus exert anti-inflammatory effects.
Hemostasis
Caffeic acid is a natural flavonoid compound that can promote vasoconstriction and the generation of coagulation factors. It also has the effect of inhibiting fibrinolysis and increasing capillary permeability, thereby playing a hemostatic role. Commonly used in clinical practice to treat hemorrhagic diseases caused by various reasons, such as gastrointestinal bleeding, nosebleeds, excessive menstruation, etc. Caffeic acid can also be added to various preparations, such as compound Danshen tablets, compound Danshen drop pills, etc., to achieve hemostasis.
Antioxidant
Caffeic acid is an antioxidant both in vitro and in vivo, with strong antioxidant effects that can neutralize free radicals and reduce oxidative stress damage to cells. This is of great significance for preventing and alleviating chronic diseases such as cardiovascular and cerebrovascular diseases, cancer, etc. Antioxidant effects can delay the aging process, maintain skin health and youthfulness, enhance immune system function, and enhance the body’s resistance.
Promoting Wound Healing
Caffeic acid can enhance the phagocytic ability of macrophages, accelerate the clearance of necrotic tissue and the formation of new granulation tissue, thereby promoting wound healing. When dealing with open wounds, avoid premature suturing of the wound to facilitate the use of caffeic acid to promote the natural repair process.
Anticancer
The inhibitory effect of caffeic acid on cancer cell proliferation in human HT-1080 fibrosarcoma cell line through oxidative mechanism. Some research results indicate that it inhibits carcinogenic effects, while others indicate that caffeic acid has carcinogenic effects. Oral administration of high-dose caffeic acid to rats can cause gastric papilloma. In the same study, high-dose combinations of antioxidants containing caffeic acid significantly reduced the growth of colon tumors of the same type in rats. Therefore, the anticancer effect of caffeic acid remains to be discussed.

Caffeic Acid Side Effects

Generally speaking, low-dose administration of BHB may be safe, but some people may experience symptoms such as stomach discomfort, diarrhea, constipation, and stomach pain. When using very high doses, these side effects are more likely to occur. BHB may be safe for use in the eyes and can be applied to eye drops.

Where to Buy High Quality Caffeic Acid

Henan Steeda Industrial Co.,Ltd is a Reputed Manufacturer and Supplier Supplying High Quality Pharmaceutical, Nutraceutical and Cosmeceutical Ingredients. Caffeic Acid is one of our most competitive ingredients with stocks available all year round. By providing high quality, we establish long-term relationships with our customers.

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