Citrus Polymethoxylated Flavones

What is Citrus Polymethoxylated Flavones

Polymethoxylated Flavones (PMFs) are a special type of flavonoid containing multiple methoxy groups (- CH3O), mainly derived from the citrus genus in the Rutaceae family, the Zingiberaceae plant in the ginger family, and the Artemisia annua L. plant in the Asteraceae family. Citrus fruits are the most abundant source of various PMFs, mainly found in the peel of citrus fruits and citrus leaves. Citrus Polymethoxylated Flavones have various biological activities, with significant activity in antioxidant, anti-inflammatory, and anticancer aspects. It also has pharmacological effects such as anti atherosclerosis, anti allergy, inhibiting platelet aggregation, regulating nerve center, anti mutagenesis and cardiovascular, and can be used to treat stomach diseases, liver diseases and cardiovascular diseases. Therefore, PMFs can be developed into drugs, health products, food additives, etc.

How Citrus Polymethoxylated Flavones Works

Antioxidant activity: Studies have found that PMFs mainly exert antioxidant effects by reducing intracellular ROS and lipid peroxidation, blocking Nrf2 ubiquitination, and stabilizing Nrf2 degradation.
Anti-inflammatory activity: PMFs mainly exert anti-inflammatory effects by blocking the production of inflammation related factors (such as NO, ROS, and PGE) and pro-inflammatory cytokines (such as IL-1, IL-6, and TNF – α), and targeting different signaling molecules in inflammation related pathways (such as MAPK, JAK-STAT, and AKT).
Anticancer activity: PMFs can exert their anti-cancer effects by controlling cancer cell growth, differentiation, apoptosis, migration, blocking tumor angiogenesis, and enhancing the anti-cancer effects of other agents. Some cancer-related signaling pathways, such as PI3K Akt, JAK-STA, etc., have also been shown to be regulated by PMFs.

Health Benefits of Citrus Polymethoxylated Flavones

Citrus Polymethoxylated Flavones has been associated with an array of potential health benefits, such as treating various diseases including Gastrointestinal, Liver, Cardiovascular diseases, here we will browes some of its important Health Benefits as below:
Gastrointestinal Diseases
Citrus Polymethoxylated Flavones can inhibit the growth of various bacteria and fungi, including some common pathogens in the gastrointestinal tract. Therefore, it has the effect of promoting gastrointestinal peristalsis, which can help with food digestion, improve symptoms of indigestion, and also alleviate symptoms of constipation.
Liver Diseases
Citrus Polymethoxylated Flavones has a certain hepatoprotective effect and can be used to alleviate symptoms such as liver damage, decreased appetite, and fatigue caused by liver diseases such as cirrhosis and hepatitis in patients. Moreover, it has been discovered in the medical field that drugs made from polymethoxylated flavones can be used to treat non-alcoholic fatty liver disease (NAFLD).
Cardiovascular Diseases
The research on citrus polymethoxylated flavones in cardiovascular diseases is becoming increasingly in-depth. Numerous studies have shown that PMFs have excellent performance in preventing and treating cardiovascular diseases, such as regulating blood lipid abnormalities, protecting myocardium and blood vessels, anti platelet aggregation, and regulating the central nervous system. If patients have arrhythmia, angina and other diseases, they can take citrus polymethoxylated flavones under the guidance of a doctor, which usually has certain effects.
Other Diseases
Citrus Polymethoxylated Flavones also has the effects of treating eye diseases, relieving dysmenorrhea, and improving uterine bleeding.

Citrus Polymethoxylated Flavones Side Effects

It is safe to consume Citrus Polymethoxylated Flavones from the diet, but the use of Citrus Polymethoxylated Flavones supplements or medications requires guidance from professionals. It should be noted that polymethoxylated flavones can slow down coagulation, so stop taking polymethoxylated flavones supplements at least 2 weeks before planning surgery. Pregnant and lactating women are advised not to use multi methoxy flavonoid products without authorization.

Where to Buy High Quality Citrus Polymethoxylated Flavones

Henan Steeda Industrial Co.,Ltd is a Reputed Manufacturer and Supplier Supplying High Quality Pharmaceutical, Nutraceutical and Cosmeceutical Ingredients. Citrus Polymethoxylated Flavones is one of our most competitive products with stocks available all year round. By providing superior quality, we establish long-term relationships with our clients.

Our Service

1) Payment
We accept payments through Telex Transfer, PayPal, Western Union, Letter of Credit, MoneyGram.
2) Shipping method
We offer several delivery services to suit all customer needs, such as AIR freight, DHL, FEDEX, TNT, UPS, EMS, SEA freight and others.
3) Lead time
Usually orders can be dispatched within 3 workdays by courier; 15-30 workdays by Sea.
4) Guarantee
We offer a 60 Days 100% Risk Free Guarantee for any orders. We will refund your money if our products do not meet your requirements.