Daidzein

Daidzein Reviews

Daidzein (7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one), a naturally occurring compound, is one of the main active ingredients in kudzu root, soybeans and other legumes. It is also named Phytoestrogen, k251b, K 251-6, isoaurostatin and Daizeol. Daidzein is a white to grayish white crystalline powder (crystallized from 50% ethanol) that can sublimate under high vacuum. It can be soluble in ethanol and ether. Daidzein belongs to the category of isoflavones structurally and has significant effects on anti arrhythmias, anti hypoxia ischemia, anti spasticity, estrogen secretion, promoting bone cell formation, and inhibiting cancer cell growth. Like genistein, daidzein has also been widely reported to have antibacterial and anticancer activities. Due to the above functions, Daidzein is mainly used for the addition of health foods and drugs.

How Daidzein Works

Daidzein is a major isoflavone in soybeans, which is metabolized into estrol by the gut microbiota. This metabolite exhibits stronger estrogenic activity than daidzein. Recent studies have shown that the clinical efficacy of isoflavones may be due to their ability to produce estrol in the intestine.

Health Benefits of Daidzein

There are so many Health Benefits of Daidzein, including Prevention and Treatment of Cardiovascular Diseases, Treatment of Post-traumatic Brain Syndrome, Treatment of Menopausal Syndrome in Women, Inhibiting Effect on Prostate Hyperplasia and so on, here we will browes some of its important Health Benefits as below:
Prevention and Treatment of Cardiovascular Diseases
Daidzein has the effect of preventing and treating cardiovascular diseases, mainly due to the following two reasons:
Firstly, daidzein can effectively inhibit the expression level of serum inflammatory factors in patients with coronary heart disease, so as to play an anti atherosclerosis role in order to achieve the purpose of treating coronary heart disease. In addition, daidzein can inhibit the proliferation of vascular smooth muscle cells and induce their apoptosis. Studies on various diseases such as hypertension and coronary heart disease caused by vascular smooth muscle cell proliferation have shown that daidzein can inhibit the proliferation of human umbilical artery smooth muscle cells, with an inhibition rate of up to 60%. Moreover, daidzein is more lipophilic and easily acts through the cell membrane. Therefore, daidzein has great development prospects in the prevention and treatment of cardiovascular diseases.
Treatment of Post-traumatic Brain Syndrome
Many literature reports suggest that the key to post-traumatic syndrome is cerebral ischemia and hypoxia after traumatic brain injury. The application of daidzein tablets in the treatment of 70 patients with this condition has achieved significant therapeutic effects in symptom improvement. Because daidzein tablets can effectively improve brain and nerve blood oxygen, they have good therapeutic effects on cerebral vascular lesions after traumatic brain injury. This drug mainly dilates coronary arteries, cerebral arteries, and femoral arteries, increases blood flow to the brain and limbs, weakens cerebral vascular resistance, increases cerebral microcirculation, and improves cerebral blood supply and oxygen supply.
Treatment of Menopausal Syndrome in Women
A decrease in estrogen can cause menopausal symptoms and osteoporosis. Simply supplementing estrogen has serious side effects, limiting its clinical application. In recent years, research has found that daidzein has estrogenic effects and no significant toxic side effects. A study on the application of daidzein in 76 menopausal women found that after 6 months of treatment with daidzein tablets, all 12 indicators in the treatment group improved.
Inhibiting Effect on Prostate Hyperplasia
Prostate hyperplasia is a common disease in elderly men, and drug treatment often fails due to the difficulty of achieving effective concentration of drugs at the affected area. By preparing an adult male mouse model of prostate hyperplasia and administering daidzein daily, the experimental results showed that daidzein had a significant inhibitory effect on prostate hyperplasia induced by testosterone propionate in mice; At the same time, it can significantly reduce the wet weight and prostate index of the prostate. In pathological examination, it was found that daidzein significantly reduced the degree of prostate hyperplasia in mice, approaching the normal control group. The results showed that daidzein had a significant antagonistic effect on prostate hyperplasia induced by propionate gao wan su.

Daidzein Side Effects

The side effects of daidzein mainly include irritation of the digestive tract, stimulation of the nervous system, and induction of allergic reactions, which need to be taken under the guidance of a doctor.

Where to Buy High Quality Daidzein

Henan Steeda Industrial Co.,Ltd is a Reputed Manufacturer and Supplier Supplying High Quality Pharmaceutical, Nutraceutical and Cosmeceutical Ingredients. Daidzein is one of our most competitive ingredients with stocks available all year round. By providing high quality, we establish long-term relationships with our customers.

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