Ergothioneine
Product Name | Ergothioneine |
CAS Number | 497-30-3 |
Molecular Formula | C9H15N3O2S |
Country of Origin | China |
Main Benefits | Used for Cosmeceutical |
OEM MOQ: 500 Units
Place of Origin: China
Bulk Package: 25kg/drum
Port: Shanghai, China
Payment terms: T/T, Letter of Credit, Western Union
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Ergothioneine Reviews
Ergothioneine(EGT and ERGO), Also called L-Ergothioneine,2-thio-imidazole, is a compound discovered in 1909, originally found in a fungus called Claviceps purpurea. The pure product is a white crystal, water-soluble. Ergothioneine is mainly present in red blood cells and the semen of certain animals. Studies have found that Ergothioneine is also present in cereal plants, and it is a common component of many microbial cells. In some edible mushrooms, such as Boletus edulis, mushrooms, and Phantom pilosula, the precursor histidine trimethyl lactone required for the synthesis of Ergothioneine can also be produced. The preparation methods of Ergothioneine sulfur include chemical synthesis, extraction, and biological fermentation synthesis. Ergothioneine is a natural antioxidant that has various physiological functions such as clearing free radicals, detoxifying, maintaining DNA biosynthesis, normal cell growth, and cellular immunity.
How Ergothioneine Works
Ergothioneine could protect and maintain the biological activity of other antioxidants in cells. It could also protect cell membranes and mitochondrial membranes from oxidative damage, and protect cells from UV radiation and other functions. And Ergothioneine can directly capture free radicals, activate peroxidase, chelate divalent metal ions (such as copper ions) to promote the clearance of free radicals and inhibit the catalytic oxidation of copper ions.
Health Benefits of Ergothioneine
Ergothioneine is a colorless and odorless natural amino acid derived from plants and can accumulate in animals. There are so many Health Benefits of Ergothioneine, such as Antioxidant and Anti Radical Effects, Anti Inflammatory Effects, Whitening Effect, Sunscreen Effect, Synergism and so on, here we will browes some of its important Health Benefits as below:
Antioxidant and Anti Radical Effects
The key to antioxidation is to fight against radicals. Ergothioneine can enter cells and mitochondria through transport proteins produced by the skin, directly clearing the antioxidant enzymes of reactive oxygen species, exerting antioxidant functions, and protecting mitochondria. In addition, multiple studies have shown that Ergothioneine can protect DNA and proteins from oxidative damage. In many cellular level biochemical reactions, Ergothioneine is considered 6000 times more effective than vitamin E. And compared to the two veteran antioxidant players, vitamin C and glutathione, Ergothioneine is milder and more stable.
Anti Inflammatory Effects
Inflammation is the body’s response when the skin is infected, and its main causes are excessive ultraviolet radiation, excessive pressure, etc. Research has shown that Ergothioneine can have anti-inflammatory effects in skin cells, mainly because Ergothioneine is a powerful hypochlorite scavenger (HOCL) that can quickly react with hypochlorite, thereby protecting red blood cells from the harm of neutrophils from normal functioning or pathological inflammatory sites. In addition, Ergothioneine can also achieve the treatment of inflammation by inhibiting the oxidation of amino acids mediated by peroxynitrite anions, such as tyrosine nitration.
Whitening Effect
The whitening effect of Ergothioneine is mainly reflected in two aspects. Firstly, it is because Ergothioneine is a natural antioxidant with high cellular protection. When their concentration reaches a certain level in certain tissues, it can stimulate the natural antioxidant defense system of cells, hinder pigment formation and deposition, and whiten the skin. Secondly, Ergothioneine can achieve whitening effects by inhibiting the accumulation of melanin. Lycase can inhibit the accumulation of melanin and achieve skin whitening. Research has shown that Ergothioneine reduces melanin, brightens skin tone, and whitens skin by inhibiting the activity of tyrosinase.
Sunscreen Effect
Ultraviolet rays are one of the culprits causing skin aging. The ultraviolet rays (UVA) in sunlight can penetrate the dermis of the human skin, affecting the growth of epidermal cells, causing surface cells to age and die, leading to premature aging of the skin, rough and loose skin, pigmentation, etc. UVB rays are also prone to the occurrence of skin cancer. Due to its absorption wavelength similar to DNA, Ergothioneine can minimize the formation of reactive oxygen species and protect cells from radiation damage. Therefore, Ergothioneine can be added as a skin protectant to certain cosmetics for the development of outdoor skincare products and protective cosmetics.、
Synergism
Ergothioneine can regulate intracellular redox reactions and participate in intracellular energy regulation. It is a physiological protective agent for cells, with biological and pharmacological properties and safety and stability. Therefore, adding Ergothioneine to a product can not only maintain the stability of other components, but also promote the absorption of active ingredients by cells, with a good synergistic effect, effectively enhancing the efficacy of its other components, achieving a 1+1>2 effect.
Ergothioneine Side Effects
Oral Ergothioneine may have some side effects, such as causing allergic reac such tionsas Rashes, breathing difficulties, skin itching, swelling, hypotension, headaches, etc. and affecting the absorption of vitamin B12 in the body.
Where to Buy High Quality Ergothioneine
Henan Steeda Industrial Co.,Ltd is a Reputed Manufacturer and Supplier Supplying High Quality Pharmaceutical, Nutraceutical and Cosmeceutical Ingredients. Ergothioneine is one of our most competitive ingredients with stocks available all year round. By providing high quality, we establish long-term relationships with our customers.
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Product Name | Ergothioneine |
CAS Number | 497-30-3 |
Molecular Formula | C9H15N3O2S |
Country of Origin | China |
Appearance | Powder |
GMO Status | NON-GMO |
Allergen | Allergen Free |
Sterilization | Non-Irradiated |
Grade | Could Meet Pharma Grade, Food Grade, Cosmetic Grade and Feed Grade |
Shelf Life | 2 Years if Sealed and Store away from Direct Sun Light |