N-Acetylneuraminic Acid

N-Acetylneuraminic Acid Reviews

N-Acetylneuraminic Acid (Neu5Ac or NANA), also known as sialic acid (SA), is a negatively charged ion that produces a smooth sensation in saliva and is also the main active ingredient of bird’s nest. It was originally isolated from bovine submandibular gland mucin, also known as sialic acid or bird’s nest acid. Mainly derived from breast milk, milk, sheep milk and other dairy products, with breast milk and colostrum having the highest content. It is a naturally occurring carbohydrate, usually present in the form of oligosaccharides, glycolipids, or glycoproteins. It is not only a neurotransmitter for gangliosides, but also a component of the brain that has the function of “inducing” invasion of bacteria. Due to its physiological multifunctionality, N-Acetylneuraminic acid is mainly used in infant formula, food ingredients, nutritional supplements, cosmetics and other fields.

How N-Acetylneuraminic Acid Works

N-Acetylneuraminic acid is one of the important monosaccharides that make up oligosaccharides in biofilms. It mostly binds to membrane proteins and forms a layer of polysaccharide protein complexes with sugar residues distributed on the surface of the plasma membrane. These glycoproteins are related to the surface behavior of most cells, and the interaction between cells and the surrounding environment involves glycoproteins. Therefore, some people compare the carbohydrate part of the cell membrane to the antenna on the cell surface, which plays an important role in receiving external information and recognizing each other between cells.
Research has found that N-Acetylneuraminic acid is related to many biological functions of organisms. As a viral receptor, it is closely related to cell malignancy, cancer metastasis, infiltration, loss of contact inhibition, decreased cell adhesion, and antigenicity. N-Acetylneuraminic acid in breast milk provides immunity for early growth in infants. The N-acetylneuraminic acid on cell membrane proteins plays a crucial role in improving cell recognition ability, detoxifying cholera toxin, preventing E. coli infection, and regulating the half-life of blood proteins.

Health Benefits of N-Acetylneuraminic Acid

N-Acetylneuraminic acid has been proven to have numerous biological functions, including promoting brain development, antiviral activity, enhancing immunity, regulating blood sugar levels, glycoprotein lysis protection, antioxidant activity, and drug precursors. Here we will browes some of its important Health Benefits as below:
Promoting Brain Development
N-Acetylneuraminic acid plays a role in regulating gangliosides in the brain, binding ganglioside proteins in the gray matter of the frontal cortex to N-Acetylneuraminic acid, increasing synaptic formation, and promoting brain development in babies. In addition, due to the presence of N-Acetylneuraminic acid, the concentration of calcium, potassium, and sodium ions in the brain can ensure physiological needs and enable brain cells to have vitality. Moreover, research has found that the golden period of human brain development occurs from pregnancy to the age of 2. This stage is a critical period for adjusting the number of brain cells, increasing their volume, improving their function, and forming a neural network. N-Acetylneuraminic acid can play a role in the transmission of electrical signals on the surface of brain cells, serving as a neurotransmitter for information transmission. The speed and quality of information transmission determine a person’s reaction speed and memory function. Therefore, adequate intake of N-Acetylneuraminic acid during pregnancy is crucial for fetal development.
Antiviral
N-Acetylneuraminic acid can to some extent protect the tissue cells of babies from virus attacks and prevent protein tissue from being degraded. N-Acetylneuraminic acid competitively binds with pathogenic bacteria, toxins, and viral ions entering the intestine, forming a stable substance that prevents intestinal toxins, pathogenic bacteria, and viral ions from binding to intestinal mucosal cells, protecting the body from attack.
Developing Immunity from Disease
N-Acetylneuraminic acid is considered an immune modulator that can help balance the body’s immune system response. Research has shown that N-Acetylneuraminic acid can prevent viruses from entering cells and causing infections by binding to viral surface proteins. In addition, N-Acetylneuraminic acid can also activate natural killer cells within cells, which can recognize and attack abnormal cells, playing a role in preventing tumor occurrence.
Regulating Blood Sugar Levels
It has the function of assisting in regulating blood sugar levels. The content of sialic acid in diabetes patients may be low, which may lead to insulin resistance and difficulty in blood sugar control. Sialic acid supplementation can help improve blood sugar control in patients with diabetes and reduce the risk of complications.

N-Acetylneuraminic Acid Side Effects

N-Acetylneuraminic acid has not yet been found to have any side effects, so it is still very safe.

Where to Buy High Quality N-Acetylneuraminic Acid

Henan Steeda Industrial Co.,Ltd is a Reputed Manufacturer and Supplier Supplying High Quality Pharmaceutical, Nutraceutical and Cosmeceutical Ingredients. N-Acetylneuraminic Acid is one of our most competitive ingredients with stocks available all year round. By providing high quality, we establish long-term relationships with our customers.

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