Nonivamide

Nonivamide Reviews

Nonivamide, also called Nonyl Vanillylamide, pelargonic acid vanillylamide (PAVA), is an organic phenolic compound and a capsaicinoid. Nonivamide, an alkaloid from the Capsicum species, is found in herbs and spices. However, the majority of Nonivamide comes from synthesis rather than extraction from natural plant sources and it was first synthesized by Nelson in 1919. Furthermore, it is an amide of pelargonic acid (n-nonanoic acid) and vanillin amine, which has antibacterial, antioxidant, anti-tumor, anti-inflammatory and analgesic effects. It is widely used in food additives, agriculture, animal husbandry, paint industry, and military fields, and as a low-cost substitute for capsaicin some formulations in the pharmaceutical industry, it has high application value.

How Nonivamide Works

Nonivamide mainly inhibits cyclooxygenase, thereby reducing the synthesis of prostaglandins, achieving anti-inflammatory, analgesic, anti rheumatic, and promoting blood circulation effects.

Health Benefits of Nonivamide

There are so many Health Benefits of Nonivamide, including Analgesic Effect, Anticancer Effect, Anti-inflammatory Effect, Weight Loss and other Effects, here we will browes some of its important Health Benefits as below:
Analgesic Effect
Nonivamide can serve as an analgesic for treating various types of pain, effectively relieving various types of pain such as arthritis, toothache, headache and neuralgia. The main principle of its analgesic effect is to inhibit the relevant receptors during the pain transmission process and prevent the transmission of pain signals. Moreover, the analgesic effect of nonivamide is comparable to that of traditional opioid drugs, but it avoids problems such as opioid addiction and significant side effects. Therefore, nonivamide plays an important role in non addictive analgesic treatment.
Anticancer Effect
The nonivamide can alter the gene related expression of tumors. It inhibits the lipid peroxidation reaction of aflatoxin B1 on the liver, thereby reducing its damage to the liver. Nonivamide is effective in the treatment of human hepatocellular carcinoma. Nonivamide has anti male prostate cancer cell effects, and it is expected to become a substitute for chemical drugs for treating prostate cancer.
Anti-inflammatory Effect
Nonivamide has good anti-inflammatory effects and can effectively alleviate inflammatory reactions. Its anti-inflammatory mechanism is mainly related to its inhibition of the release of inflammatory factors and regulation of immune system function. The anti-inflammatory effect of nonivamide has won widespread application in the treatment of autoimmune diseases such as rheumatism. By inhibiting the inflammatory response, it can effectively alleviate muscle and joint pain caused by rheumatism, and improve the quality of life of patients.
Weight Loss
Nonivamide can promote lipid metabolism, dissolve fat, and inhibit fat accumulation in the body. After nonivamide enters the human body, it can promote the secretion of neurotransmitters acetylcholine and norepinephrine, while adrenaline can have a more effective weight loss effect by sweating and burning fat.
Other Effects
In addition to the above effects, nonivamide also has various therapeutic uses. For example, it also has therapeutic effects on chilblains, baldness, etc., because nonivamide can dilate blood vessels, promote microcirculation and hair growth. In addition, it has antibacterial, antipruritic, bactericidal and other effects, and can be used to prepare various topical drugs. Mainly because nonivamide can stimulate nerves to release CGRP and SP, which can effectively treat skin neuroinflammation and prurigo. What’s more, it also has various biological activities such as antioxidation, prevention of cardiovascular diseases, promotion of digestion, and enhancement of immunity, and has great potential for development in the field of medicine.

Nonivamide Side Effects

Nonivamide generally has the effect of promoting appetite and accelerating metabolism, but may cause side effects such as nausea and vomiting.

Where to Buy High Quality Nonivamide

Henan Steeda Industrial Co.,Ltd is a Reputed Manufacturer and Supplier Supplying High Quality Pharmaceutical, Nutraceutical and Cosmeceutical Ingredients. Nonivamide is one of our most competitive ingredients with stocks available all year round. By providing high quality, we establish long-term relationships with our customers.

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