Pterostilbene

Pterostilbene Reviews

Pterostilbene, also called ” 3′,5′-Dimethoxy-4-hydroxystilbene “, is a kind of stilbene compounds and can be regard as O-methyl derivatives of resveratrol, which has similar pharmacological effects to resveratrol. It was found in various plants such as rosewood, blueberries, grapes, and palm trees. Pterostilbene comes from plants such as redwood, blueberries, grapes, and palm trees. It is a white or almost white powder crystal with rich medicinal value. It belongs to the antifungal active ingredient in dragon’s blood products and has anti-cancer, anti-inflammatory, antioxidant, anti-tumor, lipid-lowering, antibacterial, and analgesic effects.

How Pterostilbene Works

The mechanism of action of Pterostilbene is believed to be its antioxidant properties. Pterostilbene can reduce the production of oxidative stress (OS) and reactive oxygen species (ROS), such as hydrogen peroxide (H202) and superoxide anion (02-), which are related to the occurrence and pathogenesis of various disease processes. Pterostilbene can inhibit the development of malignant cells and improve normal cell function.

Health Benefits of Pterostilbene

There are so many Health Benefits of Pterostilbene, including Cardiovascular Maintenance, Liver Protection, Metabolism, Neuroprotection and UV Resistance, here we will browes some of its important Health Benefits as below:
Cardiovascular Maintenance
Research has found that the main cause of cardiovascular disease is dysfunction of endothelial cells, increased mechanical stress on the endothelium and reactive oxygen species produced by white blood cells can accelerate damage. The increase in endothelial mechanical stress can easily lead to vascular damage and thrombosis. The antioxidant mechanism of the human body itself is imbalanced with the production of free radicals, therefore, daily consumption of antioxidants may have a protective effect on vascular damage. Research has shown that Pterostilbene is beneficial to the cardiovascular system and can delay the aging of endothelial cells and mitochondrial oxidative stress. This is because Pterostilbene helps reduce the damage of free radicals, has strong antioxidant effects, and can also regulate antioxidant enzymes and defense systems throughout the body.
Liver Protection
The pathogenesis of chronic liver disease is complex, but the development trend of the disease mainly ranges from acute liver cell damage to cell apoptosis, necrosis, inflammation, and irreversible fibrosis, ultimately leading to cancer. However, regardless of the cause, oxidative stress is a common mediator for liver injury to develop into sustained inflammation and fibrosis. Many pieces of evidence suggest that Pterostilbene can promote liver cell function by altering various antioxidant, anti-inflammatory, and anti proliferative mechanisms. The main principle is that Pterostilbene can inhibit the expression of COX-2, iNOS, PGE2, and NO through the Nrf2 pathway, reducing the degree of inflammation. Pterostilbene can also downregulate the inflammatory response and reactive oxygen species (ROS) in cells. In addition to its role in clearing ROS, it also has inhibitory effects on the activation of neutrophils, production of inflammatory mediators, and apoptosis of endothelial cells.
Metabolism
Diabetes is also a kind of “metabolic syndrome”, the cause of which is carbohydrate, fat and protein metabolism disorder caused by ineffective regulation of insulin. According to research reports, the antioxidant and anti hyperglycemic activities of Pterostilbene can be used to improve hyperglycemia and related liver and kidney damage, which is beneficial to diabetes patients from complications. Although the relationship between the antioxidant activity induced by Pterostilbene and glucose regulation has not been discovered, it is speculated that Pterostilbene can improve glucose metabolism by increasing antioxidant activity. The increase in antioxidant activity produced by Pterostilbene may reduce the damage of reactive oxygen species produced by hyperglycemia to organs.
Neuroprotection
Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, etc., are directly related to aging in their causes. This is due to the decline in antioxidant capacity and increased oxidative stress in the elderly body, which are related to aging and can exacerbate aging after onset. Multiple studies have shown that consuming berries rich in antioxidant properties can effectively improve the metabolism of this nervous system.
The antioxidant activity of Pterostilbene is the key to inhibiting the pathogenesis. Its impact on antioxidant activity and multi organ system pathogenesis is complex, but its benefits are enormous. Pterostilbene can not only protect nerves, weaken atherosclerosis, prevent hemolysis and liver diseases, but also regulate DM and hyperlipidemia. In the experiments of aging, vascular disease, diabetes and hemolysis, Pterostilbene prevents progressive cell damage and dysfunction related to disease deterioration by reducing oxidative stress.
UV Resistance
Pterostilbene is a natural sunscreen ingredient. The cream containing 0.4% Pterostilbene can provide skin with SPF 6.2 sunscreen protection. The maximum UV absorption wavelength of Pterostilbene is 306nm, covering the UVB band of 280-320nm, and it has a good UVB absorption effect. Moreover, by studying the protective effect of Pterostilbene on acute light damage to human fibroblasts caused by longwave ultraviolet radiation, researchers have found that an appropriate amount of Pterostilbene can alleviate the damage of ultraviolet radiation to human fibroblasts.

Pterostilbene Side Effects

Firstly, Pterostilbene may experience allergic reactions in certain populations. In addition, Pterostilbene may have adverse effects on the health of pregnant and lactating women. Therefore, these populations should consult their doctors before using Pterostilbene.

Where to Buy High Quality Pterostilbene

Henan Steeda Industrial Co.,Ltd is a Reputed Manufacturer and Supplier Supplying High Quality Pharmaceutical, Nutraceutical and Cosmeceutical Ingredients. Pterostilbene is one of our most competitive ingredients with stocks available all year round. By providing high quality, we establish long-term relationships with our customers.

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